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Herbs

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Formula List
AI # 3 Capsule
Allicin Capsule
Artemisia Capsule
Artemisia 2 Capsule
(Double Potency)
BM Capsule
Capillaris Combination
Circulation P Capsule
Copmine Formula
Coptis Capsule
Cordyceps Capsule
DH-Artemisinin Capsule
Gall Formula 1
Gineseng and Atractylodes Formula
Glycyrrhizin Capsule
GL2
Hepa Formula 1A
Hepa Formula 2
HerbLipido
HerbSom Capsule
HerbZac Capsule
HH Tablets
HH 2 Capsule
(Double Potency)
Ligustrin Capsule
Milk Thistle Plus
MVM Formula
Olivessence Capsule
Puerarin Capsule
R-5081 Capsule
R-OBG Capsule
Schisandra Plus
Sedin
TGP formula
Yunan Paiyao Capsule
 
HerbLipido Capsule
Recommended Daily Dose:
2 Capsules, 3 Times a Day

(Individual Dosage May Vary. Please Your Consult Health Care Professional)

 

Hyperlipidemia is a common condition in today’s population. It can cause cardiovascular problems and also the condition known as fatty liver. Fatty liver is a common pathogenesis of alcoholic liver damage, non-alcoholic steatohepatitis (NASH), and a complication of chronic viral hepatitis. Academic and clinical research studies conducted in China have found that modern Chinese medicinal herb based compounds can be effective in treating this condition and its related disorders. [1,2,3]

The basis for treatment is to reduce the serum levels of cholesterol triglyceride (TG). Most medications for lowering cholesterol and TG are harmful to the liver and unsuitable for people with pre-existing fatty liver conditions. Chronic fatty liver makes it very difficult for people to tolerate conventional pharmaceutics.

The HerbLipido Capsule is designed as an alternative remedy. It is designed to lower serum lipid level and support the functions of the liver. Many ingredients of this capsule are also used for treating chronic liver inflammations in traditional Chinese medicine (TCM). [2]

 

A. Herbal and Supplement Composition:

Hu Zhang (Polygoni Cuspidati Rhizoma), Huang Qin (Scutellariae Radix), Yu Jin (Radix Curcumae), Yin Chen Hao (Herba Artemisiae Scopariae), He Shou wu (Radix Polygoni Multiflori), Ze Xie (Rhizoma Alismatis), Bai Shao (Radix Paeoniae alba), Pu Huang (Pollen Typhae), Shan Zha (Crataegi Fructus), Jue Ming Zi (Semen Cassiae), He Ye (Folium Nelumbins), Hong qu (Monascus purpureus Went), Tea polyphenol, and Hexanicotol.

B. Pharmacology of Main Ingredients

Hu Zhang contains polydatin, which can obviously reduce serum cholesterol in animal model experiments. Huang Qin extract can reduce cholesterol level in hyperlipidemia animals. [4]

Yin Chen Hao has lowering serum cholesterol level effects. It also dilates the coronary artery and has fibrinolytic effects. It can specifically lower the level of beta-lipoprotein and reduce arteriosclerosis. [5] The above two herbs were used in TCM to treat chronic liver inflammations.

He Shou Wu reduced cholesterol levels and arteriosclerotic lesions found in animal studies [6,7]. In intestinal tracts of rabbits, the herb reduced the absorption of cholesterol [8]. The lecithin content of the herb could prevent the accumulation of cholesterol in the liver, prevent retention of lipids in the blood stream, and penetration of lipids into the arterial endothelium, thereby reducing the arteriosclerosis [6,9]. Its anti-fibrinolytic activity can prevent arteriosclerosis [9]. When given extracts of Shan Zha to rabbits, it was found that the TG and cholesterol levels were significantly lower than the control group, and the average thickness of atheromatous plaques as well as the number of the vascular lesions were smaller and milder than those of the control group. It facilitated the clearance of cholesterol but did not prevent its absorption [10].

Pu Huang has strong anti-arteriosclerosis and serum lipids reduction effects. Animal studies found that after the hyperlipidemia animals were treated with this herb, their cholesterol and TG levels were much lower than the control group and their arteriosclerosis was much milder than the control group. The cholesterol contents of the stool samples of the treated group were much higher than the control group. It was considered that the anti-hyperlipidemia effect is based on its ability to lower cholesterol absorption from the intestine and also block re-absorption of the cholesterol and bile acid from the bile in the intestine. [11,12]

Ze Xie has been studied both in China and Japan as an anti-hyperlipidemia and fatty liver therapy. It has obvious hypocholeserolemia and anti- arteriosclerosis effects in the rabbit model. It can also reduce the TG content in the liver of rabbits, which were fed high-cholesterol foods in laboratory studies. [13,14] The same effects have been seen in rat models. [15]     

 

Hexanicotol metabolizes in the body becomes nicotinic acid and inositol. Both have gentle and lasting blood lipid reduction actions. Nicotinic acid belongs to the vitamin B family. When used in larger doses, it has blood lipid regulatory effects. It can suppress free fatty acid release from fat tissue and affects the liver’s function in absorption of free fatty acid and synthesis of triglyceride (TG). It can dramatically reduce the synthesis of very low-density lipid (VLDL) in the liver and hence reduce the level of VLDL in the blood. It can also lower the level of low-density lipid (LDL). VLDL and LDL are considered as “bad” cholesterol. Its main action is to lower the level of TG. After use, TG can usually be reduced 20 to 30% from original levels. Total cholesterol can be reduced by 10% and high-density lipid (HDL) can increase slightly because it also promotes the synthesis of prostacyclin, which can suppress the clustering of platelets and dilation of small blood vessels. These effects are beneficial for treating arteriosclerosis. Inositol can reduce the fragility of the micro-capillaries and prevent fat deposits in the liver. It can help regulate blood vessel dilation and is an anti-blood vessel spasm agent. [16]

Tea polyphenol is a strong anti-oxidant that can stabilize the product; it has also an important effect in preventing liver cell membrane damage caused by steatohepatitis.

        

C. Clinical Studies done in China

The herbal formulas based on above herbal contents have been used for treating coronary disease and hyperlipidemia in China. The effects are lowering the serum cholesterol level, decreasing platelet adhesion, and symptom-relief of coronary disease. The effective rate was approximately 70 to 80%. It also lowers the level of TG in the serum.  While used for coronary disease, the EKG improvement rate was 48.8%. [8,9,14] Formula contents in the above herbs have been successfully used for treating NASH. Its effects were not only seen in reducing the serum lipid levels but also demonstrated decreased the serum endotoxin and tumor necrosis factor. [18] Ze Xie has been used as a single herb remedy for hyperlipidemia and fatty liver, and its potency was found to be similar to Atromide-S but without the side effects. [19,20] In a study of 181 cases treated with Zixie tablet for a one to three months course, 154 of the patients showed a marked decrease of blood cholesterol and TG in 89.6% and 74.7% respectively. Cholesterol was lowered by a mean of 44.84mg and TG by 32.5mg. The efficacy of this tablet was generally similar to that of clofibrate. Patients experienced improvement of symptoms, such as dizziness, disorientating sensations in the head, and chest discomfort. [21,22]

 

D. Dose and Suggested use:

Every capsule contains 500mg of the extracts of the formula.
Take 2 capsules three times a day.

Package: Each bottle contains 90 capsules, 15-day supply.

 

 

References

[1] Li YM, About Non-alcoholic Lipoidal Liver Disease, Chin J Integra Trad & West Med, 2004, 24(1):11

[2] Hu YY, To Strengthen Further Study on Treatment of Lipoidal Liver Diseases by Traditional Chinese Medicine, Chin J Integra Trad & West Med, 2004, 24(1):12

[3] Ji Guang, et al., Clinical Study on Treatment of Alcoholic Liver Disease by Qinggan Huoxue Recipe, Chin J Integra Trad & West Med, 2004, 24(1):13-17

[4] Qing ZF et al., Pharmaceutics Journal, 77:1303, 1957

[5] Zhejiang Medical University, Second Teaching Hospital Cardiovascular Research Department, Treating Coronary Heart Diseases with Yin Chen Hao. Proceedings National Conference on Coronary Heart Diseases, Shanghai, 1979

[6] Tongren Hospital of Beijing, References on medicine and health, 1963. p.1

[7] Neimenggu Autonomous Region Hospital, Proceedings of the symposium on geriatrics, 1964

[8] Beijing Region Coordinating Research Group on Prevention and Treatment of Coronary Diseases, Annual Research Report, 1971

[9] Information Department of Hunan Institute of Medical and pharmaceutical Industry. Chinese Traditional and Herbal Drugs Communications, 1977(4):48.

[10] Pharmacology, Pathology, and Combined Western and Traditional Chinese medicine Research Units, Jiangsu College of New Medicine, Compiled Information, 1975(1):16

[11] Ding T et al., Experimental Atherosclerosis of Rabbits Treated with Typha Pollen, Shanghai Medical Journal, 1980, (8):53 

[12] Shanghai Second Medical College, Trends on the Studies of the Blood-Stimulant and Stasis-Eliminative Actions of Typha Pollen, Development in Scientific Research, Vol. 5, 1975

[13] Koboyashi T., Journal of the Pharmaceutical Society of Japan (Tokyo) 1960, 80(10):1460

[14] Koboyashi T. Journal of Parmaceutical Society of Japan (Tokyo) 1960,80(11):1617

[15] Tadakazu M. Chem Pharm Bull, 18:1347, & 1369, 1970

[16]  YC, Practical Manual of Medication, Chunghwa Book, Hong Kong, 2002, p.232

[17] Clinical Research Dept, Hunan Institute of TCM, Hunan Information on Science and Technology, 1979 (3):5

[18] Qi XH et al., Experimental Study of Chitosan with TCM compound Reducing Hepatic-Lipid in Rats, Chin J Inter Tradi & Western Med on Liver Diseases, 2003, 13(5):275-277

[19] Wang LW, et al., Acdemica of Dalian Medical College, (1):40,1965

[20] Zhongshan Hospital of Shanghai First Medical College, Chinese J of Medicine, (11):693, 1976

[21] Wang LW et al., Acta Academiae Medicinae Dalian 1965 (1):40

[22] Zhongshan Teaching Hospital of Shanghai First Medical College, National Medical J of China, 1976 (11):693