Recommended Daily Dose:
1 Capsule, 2 Times a Day
(Individual Dosage May Vary. Please Your Consult Health Care
uralensis Fisch (licorice root)
GL consists of
triterpenes glycyrrhizin and glycyrrhetinic acid, usually as salts of
glycyrrhizic acid and ammonia, calcium, potassium, iron, or barium. The
glycyrrhizin capsule we use is a potassium salt of glycyrrhizic acid.
Licorice is the most
frequently used herb in Traditional Chinese Medicine (TCM) and has been
extensively studied. TCM classifies licorice as a sweet, mild herb and
uses it to supplement the body, clear "latent heat," regulate
stomach functions, expectorate the lungs, and invigorate the spleen. It
has been used as an antipyretic, detoxicant, and anti-inflammatory. Many
TCM formulas use licorice as a corrective adjutant and harmonizing
ingredient. Clinically, it is used for cough, palpitation, stomachache,
peptic ulcer, phyogenic infection, and skin rashes.
· Anti-viral effects: GL
induces the generation of interferon-gamma in test animals and in humans.
It can prolong the survival of mice following injection with hepatitis
virus MHV. In rabbits, it can inhibit virus proliferation. Seventeen
hospitals in China have studied the therapeutic effects of GL on 300 cases
of hepatitis B. The clinical curative rate was 44% and the effectiveness
rate was 77%, with 41% of the patients seeing their HBeAg serum positive
status convert to negative. Treating viral hepatitis with GL can
significantly shorten the disease course, accelerate recovery of liver
function, normalize ALT and AST, and turn HBeAg to negative in about 40%
of patients. Studies in Japan have confirmed these effects.
· Protecting and healing liver
cells from chemical and biological injuries: GL can alleviate histological
disorder due to inflammation and restore liver structure and function from
damage due to carbon tetrachloride. The effects include lowering ALT (SGPT):
64% with normalized ALT following administration in a Japanese study and
87% in a study conducted in China. GL can reduce degeneration and
necrosis, and recover glycogen and RNA of liver cells. Experimental
hepatitis and cirrhosis studies on rats found that GL can promote the
regeneration of liver cells and inhibit fibrosis. It can also reduce
gamma-globulin and interstitial inflammation in the liver.
effects: Anti-allergic, anti-inflammatory, and detoxifying activities are
all important for its use in treating viral hepatitis. Its anti-allergic
and anti-inflammatory activities resemble the activities of glucocorticoid,
since GL maintains the level of active corticoid in the blood and
increases endogenous corticoid by inhibiting deactivation of
glucocorticoid in the liver. Further, GL promotes the regeneration of
inflammatory tissue in contrast with glucocorticoid, which inhibits
regeneration. GL also inhibits the release of histamine from mast cells.
Although licorice is a non-toxic herb, long-term use can cause some
adverse reactions in about 20% of patients. Edema, elevated blood
pressure, low blood potassium, dizziness, and fatigued limbs may be seen.
Patients with hypertension (high blood pressure) should not take