Herb Distribution @

Zhang Clinic
20 E. 46th Street
Suite 1402
New York,  NY 10017

Tel:  (212) 573-9584 
Fax: (212) 573-6045

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Hepatitis C
Lyme Disease
Hepatitis Peripheral Complications Colitis /Crohn's Disease (Inflammatory Bowel Syndrome)
Non-Alcoholic Steatohepatitis (NASH): Fatty Liver Liver Cirrhosis Related Conditions
Alcoholic Liver Disease  
Auto-Immune Hepatitis
Cholestatic Hepatitis
SinoMed Research Home
About Dr. Zhang

ZHANG CLINIC featured again in
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Formula List
AI # 3 Capsule
Allicin Capsule
Artemisia Capsule
Artemisia 2 Capsule
(Double Potency)
BM Capsule
Capillaris Combination
Circulation P Capsule
Copmine Formula
Coptis Capsule
Cordyceps Capsule
DH-Artemisinin Capsule
Gall Formula 1
Gineseng and Atractylodes Formula
Glycyrrhizin Capsule
Hepa Formula 1A
Hepa Formula 2
HerbSom Capsule
HerbZac Capsule
HH Tablets
HH 2 Capsule
(Double Potency)
Ligustrin Capsule
Milk Thistle Plus
MVM Formula
Olivessence Capsule
Puerarin Capsule
R-5081 Capsule
R-OBG Capsule
Schisandra Plus
TGP formula
Yunan Paiyao Capsule
Ligustrin Capsule
Recommended Daily Dose:
One Capsule, 3 Times a Day

(Individual Dosage May Vary. Please Your Consult Health Care Professional)

Original Herb:

Ligustrum Fructus (Ligustrum lucidum Ait)

Traditional Use:

Traditional Chinese Medicine uses ligustrum as a tonic for the liver and kidneys, principally as a treatment of symptoms associated with "yin deficiencies," such as dizziness, blurred vision, tinnitus, premature graying of hair, and low-back ache.

Chemical Composition:

Ligustrin is a highly purified extract of Ligustrum lucidum Fructus. Its major chemical component is oleanolic acid. Other components include acetyloleanolic acid, betulin, lupeol, salidroside, mannitol, oleic acid, linolenic acid, and palmitic acid.

Pharmacological Actions:

Ligustrin protects the liver from chemical and biological injuries through the following actions.

     Ligustrin helpe lower the liver enzyme ALT (SGPT) level. In experimental cirrhosis studies, ligustrin inhibited degeneration and reduced necrosis of liver cells. It can increase glycogen in the liver, accelerate repair of necrosed tissue, and promote regeneration of liver cells. It can also inhibit inflammation and collagen formation.

     Ligustin raises the WBC count and is used to treat leukopenia caused by radiation and chemotherapy.

     In clinical trials for treating acute or chronic hepatitis, it can rapidly reduce ALT, AST, and jaundice; it has a 90% clinical cure rate for acute icterohepatitis and a 70% effectiveness rate for chronic hepatitis.

     Ligustrin has immune-regulatory effects, specifically, it promotes lymphoblast cell transformation, suppresses Ts cells, increases Th cells, and promotes phagocytosis of macrophages.

      Ligustrin can increase coronary blood flow.

     Acute and chronic toxicity tests have shown that ligustrin has very low toxicity. After injecting dogs with 50mg/kg IV and mice with 5mg/20g IV, 24 hours of observation found no adverse reactions. After injecting rabbits with 50mg/kg IP daily for 6 to 12 weeks, no heart, liver, or kidney disorders were found.