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Zhang Clinic
20 E. 46th Street
Suite 1402
New York,  NY 10017

Tel:  (212) 573-9584 
Fax: (212) 573-6045

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Hepatitis C
Lyme Disease
Hepatitis Peripheral Complications Colitis /Crohn's Disease (Inflammatory Bowel Syndrome)
Non-Alcoholic Steatohepatitis (NASH): Fatty Liver Liver Cirrhosis Related Conditions
Alcoholic Liver Disease  
Auto-Immune Hepatitis
Cholestatic Hepatitis
SinoMed Research Home
About Dr. Zhang

ZHANG CLINIC featured again in
Dr. Weil's "Self Healing" newsletter

Click here to read the excerpt

Formula List
AI # 3 Capsule
Allicin Capsule
Artemisia Capsule
Artemisia 2 Capsule
(Double Potency)
BM Capsule
Capillaris Combination
Circulation P Capsule
Copmine Formula
Coptis Capsule
Cordyceps Capsule
DH-Artemisinin Capsule
Gall Formula 1
Gineseng and Atractylodes Formula
Glycyrrhizin Capsule
Hepa Formula 1A
Hepa Formula 2
HerbSom Capsule
HerbZac Capsule
HH Tablets
HH 2 Capsule
(Double Potency)
Ligustrin Capsule
Milk Thistle Plus
MVM Formula
Olivessence Capsule
Puerarin Capsule
R-5081 Capsule
R-OBG Capsule
Schisandra Plus
TGP formula
Yunan Paiyao Capsule
MVM Liver Formula

Supplement Facts:

Serving size: 2 tablets

Servings per container: 60

2 tablets, 2 times per day provide:

% Daily Value

Vitamin C (as Ester-C®)

180 mg


Vitamin E (as d-alpha tocopherol succinate)

400 IU


Vitamin K

80 mcg


Thiamin (as thiamin mononitrate)

3 mg



3.4 mg


Niacin (as niacinamide)

20 mg


Vitamin B6 (as pyridoxine HCl)

5 mg


Folate (as folic acid)

800 mcg


Vitamin B12 (as cyanocobalamin)

500 mcg



600 mcg


Pantothenic acid

20 mg


Calcium (as calcium amino acid chelate)

200 mg


Iodine (from Atlantic kelp)

150 mcg


Magnesium (as magnesium amino acid chelate)

100 mg


Zinc (as zinc amino acid chelate)

15 mg


Selenium (as selenium amino acid complex)

100 mcg


Copper (as copper amino acid chelate)

2 mg


Manganese (as manganese amino acid chelate)

2 mg


Para-Aminobenzoic acid

20 mg



50 mg


Alpha-lipoic acid

100 mg


Glutathione (reduced)

5 mg


*Daily Value not Established

Other Ingredients: Cellulose, stearic acid, cellulose gum, magnesium stearate and silicon dioxide.


Directions: As a dietary supplement, take 2 tablets, 2 times daily, with meals.

Storage: Keep tightly closed, in a cool dry place.


Introducing A Specially Designed Multiple Vitamin and Mineral Supplement for People with Liver Disorders

Many patients with liver disorders ask me what are the proper vitamins and mineral supplements they should take to help them maintain good health. To meet their request, I have asked Dr. Stephen Paul, Ph D. of biochemistry and an authority in dietary supplement industry, to design a special formula that can be safely and effectively used by people with liver disorders. He has completed his research and formulated the MVM Liver Formula. The HepaPro Corporation has adopted this product into their line of supplements. The following is an explanation given by Dr. Paul on the ingredients of this formula and why they are beneficial for people with liver disorders.

Dr. Qingcai Zhang

MVM Liver Formula

MVM Liver Formula is specially formulated to protect and strengthen the liver, replenish nutrient deficiencies and boost general immunity. It contains nutrients that have been shown to be safe and effective when used as recommended, by people with hepatitis and other liver disorders.

While a good diet provides adequate supplies of nutrients for most healthy people, patients with hepatitis and other liver disorders often have vitamin and mineral deficiencies.


The B vitamins are all required for the normal functioning of specific enzymes. They are responsible for many important processes such as converting sugar into usable energy and keeping cells healthy. Because these vitamins are vital to a vigorous long life, not getting them can lead to serious problems. Especially for patients with liver disorders, fatigue is the most common symptom and with the help of B vitamins the energy generating mechanism in the liver will be functioning well and can help to release this symptom.

B vitamins provide:

· improved liver health

· improved health of the skin, bones, hair and muscle

· health of the mucosal membranes, particularly around the mouth

· intestinal health and bowel function

· relief of moodiness, restlessness, irritability, insomnia and fatigue

· enhanced brain cell function and health

· relief from skin problems, including dry and itchy skin and rashes

· relief from PMS

B complex vitamins are often recommended for liver problems. They support certain detoxification pathways in the liver.

Thiamin (Vitamin B1) is often deficient in patients with liver disease. Thiamin aids in the proper function of the mucous membranes, nervous system, muscles, heart, and metabolism.  It aids energy levels, decreases pain, and may fight viruses (e.g., Herpes Zoster). Symptoms of thiamin deficiency include poor memory, fatigue, muscle weakness and blindness. These symptoms are also common in liver disorders. Over time, thiamin deficiency can lead to heart disease and brain damage.

Riboflavin (Vitamin B2) enables carbohydrates, proteins, and fats to release energy. Riboflavin is needed for normal reproduction, growth, and repair of skin, hair, nails, and joints. It is also important to the immune system.

Niacinamide (Vitamin B3) is necessary for utilization of fats, tissue respiration and production of polysaccharides. This vitamin aids in release of energy from foods, helps synthesize DNA. It is also involved in the manufacture of sex and adrenal hormones.

Pantothenic acid (Vitamin B5) is needed for certain detoxification processes in the liver as well as conjugation of bile acids produced by the liver. Bile acids must be conjugated in order to help in the assimilation of dietary fats.

Pyridoxine (Vitamin B6) has a wide variety of metabolic functions in the body, especially in amino acid metabolism and in the central nervous system, where it supports production of gamma-aminobutyric acid (GABA). Pyridoxine deficiency causes blood, skin, and nerve changes. This vitamin is unique in that both deficiency and excess can cause peripheral neuropathy. Pyridoxine is needed for proper immune function. Deficiency of this nutrient impairs immunity. Hepatitis and liver disorders increase the risk of pyridoxine deficiency.

Vitamin B12 promotes healthy blood cells, appetite and mental function. Because the liver is involved absorption of Vitamin B12, a diseased or inflamed liver may not be able to keep up with body demands for this vitamin under stress. B12 is needed to help cells grow and maintain normal function. It is an especially important vitamin for healthy bone marrow (where blood cells are formed) and the nervous system. Not getting enough Vitamin B12 leads to a condition called pernicious anemia, which results in red blood cells not getting enough oxygen and causing disorders of the nervous system.

Supplementation with folic acid along with vitamin B12 has shown promise in helping to reduce the number of days of hospitalization from viral hepatitis and to speed healing of the injured liver. Folic acid and vitamin B12 may protect against ribavirin-induced anemia, which occurs in 10 percent of hepatitis C patients being treated with ribavirin.

Biotin is required for fat and protein metabolism, effective immunity and gene function. Biotin deficiency is most common in the elderly, people with diabetes and in those who take too many antibiotics. Anemia, muscle pain, dermatitis and pins-and-needles in the toes mark biotin deficiency.


Vitamin C provides general support for the immune system. It also is required for the production of the protein known as collagen. Collagen found in all tissues of the body. Also found in the filtration apparatus of the kidneys, which can be diseased in hepatitis patients. High doses of vitamin C (greater than 2,000 mgs per day) can cause increased absorption of iron from the bowel and is thus contraindicated in people with high levels of iron in their liver cells, which are common in chronic hepatitis patients. High iron level is being considered to have negative effects on the healing of the liver.


People with hepatitis are often deficient in Vitamin E, and this deficiency will weaken the immune system, weaken the red blood cells, and worsen the nerve and muscle damage that can occur with hepatitis. Vitamin E is a powerful antioxidant. It helps overcome fatigue and enhances cell mediated immunity. Vitamin E deficiency is linked to cirrhosis. Vitamin E may prevent some of the molecular changes associated with the development of cirrhosis.


Vitamin K deficiency is associated with liver disease. Poor blood clotting is a symptom of deficiency. Vitamin K is a key cofactor for the formation of a number of proteins that include -carboxyglutamic acid. The best recognized of these is prothrombin. However, it is now recognized that carboxylation is an important enzymatic step for the activation of a wide range of proteins with many different functions. These proteins are in the blood, kidney, lung, and bone. It has been recently recognized that vitamin K plays a role in bone formation. Recent evidence suggests that even patients with cirrhosis may have abnormal bone turnover and increased risk of osteoporosis. Vitamin K therapy may improve bone mass among people with cirrhosis. The role of vitamin K supplementation is of greatest interest in patients with cholestatic (blockage of bile secretion) liver disease, both because these patients are at greatest risk for malabsorption of fat-soluble vitamins and vitamin K is fat-soluble.

Chronic liver disease is frequently associated with osteopenia and osteoporosis and, occasionally, osteomalacia, particularly in the setting of alcoholic and cholestatic liver disease. Recent studies suggest that even patients with chronic viral hepatitis have decreased bone mineral density (BMD) and osteoporosis. Bone disease associated with cirrhosis is multifactorial in nature and may be due to malabsorption of fat-soluble vitamins, including vitamin D, and calcium; malnutrition; and increased bone turnover from hormonal and metabolic factors. In addition to the nonspecific effects related to chronic liver disease, patients with cholestatic liver disease are at risk for malabsorption of calcium and fat-soluble vitamins such as A, D, E, and K, which may lead to osteomalacia.


Calcium is needed to boost the defense mechanism of white cells and along with other minerals such as zinc, copper and manganese for optimizing bone density.

Magnesium is a cofactor involved in a multitude of metabolic reactions. It levels can be depressed in digestion is poor as well as in people who exhibit type A behavior.

Manganese is needed of healthy bones and white cell defense mechanisms. It also may help to reduce the muscle weakness that is commonly associated with hepatitis.

Selenium is important in a number of immune functions that help the body’s ability to handle the hepatitis virus. It works synergistically with glutathione in order to maintain healthy immunity. It prevents fat oxidation, which reduces the workload of the liver. It also works with iodine to support healthy thyroid function and is useful since some hepatitis patients experience thyroid problems.

Zinc is important for bone strength. It also is a cofactor involved in many metabolic reactions and helps to maintain a healthy immune system.

Iodine supports healthy thyroid function and may be helpful since some hepatitis patients experience thyroid problems, especially hypothyroidism.


Inositol aids in cholesterol levels of blood, promote even distribution of fats around the body, combine with other ingredients in the liver to produce lecithin and also cleanse the blood of excessive fats, which can reduce the risk of fatty liver.

L-glutathione, abbreviated as "GSH", is the body’s key antioxidant and protectant. GSH has multiple functions in disease prevention and in detoxification of chemicals and drugs while its depletion is associated with increased risks of toxicity and disease. GSH works synergistically with the other cellular antioxidants to neutralize and scavenge oxygen and other free radical species and thereby prevent or diminish "oxidative stress". A deficiency of hepatic GSH and its antioxidant partners and/or an increase in toxic free radical species may contribute to the progression of liver disease.

 The nutrient alpha-lipoic acid is an antioxidant that increases production of glutathione, which helps dissolve toxic buildup in the liver so it can be flushed out through the kidneys. It also helps make vitamins C and E work better, and it speeds up the body's metabolism. ALA is a liver cell membrane stabilizer and can protect the liver cell from the injuries caused by multiple factors.

Para-aminobenzoic acid (PABA) is an important antioxidant and a component of folic acid. It stimulates intestinal bacteria, enabling them to produce folic acid, which aids in production of pantothenic acid. PABA is necessary for the metabolism of amino acids and in the formation of blood. Its deficiency is associated with depression, fatigue and indigestion.


Along with proper treatment, the specific combination of these vitamins and minerals will help ensure the long-term health of patients with chronic liver disease.