Hepatitis C
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Articles by
Dr. Zhang
 
TCM and MCM Theory Related to Common Liver Disease Blood Test Markers

Low Dose Interferon Patient Experiment

Hepatitis A Prevention Reminder

Hepatitis: Causes of Pain in Liver Region 

The Need to Monitor Your Chronic Hepatitis

Liver Enzyme Fluctuation during Allergy Season 

What are the Serum Markers of Hepatitis B and What do They Mean?

Enterogenous Endotoxemia in Chronic Hepatitis–
Part 2

Enterogenous Endotoxemia in Chronic Hepatitis–
Part 1
 

Chronic Hepatitis and "Blood Activating and Stasis Expelling" (BASE) Therapy -
Part 2

Chronic Hepatitis and "Blood Activating and Stasis Expelling" (BASE) Therapy
Part 1

What Causes Gastrointestinal Bleeding in Cirrhotic Liver Disease

Dietary Support for Cirrhotic Liver Diseases

Ascites - A Complication of De-Compensated Liver Cirrhosis

Liver Cirrhosis - Portal Vein Hypertension Complications

Liver Cirrhosis Overview

PG-IFN and Ribavirin Treatments

Antibiotics and Chronic Liver Diseases

Why is Alcohol Harmful for People with Hepatitis?

Co-infections and Super-infections of Viral Hepatitis

Beware of Medications That Can Cause Liver Damage

Bile Retention and Its Clinical Manifestations (MCM) part 4

Modern Chinese Medicine (MCM) Part 3 
Jaundice and Chronic Viral Hepatitis

Modern Chinese Medicine (MCM) Anti-Liver-Fibrosis Treatments - Part 2

Modern Chinese Medicine (MCM) Anti-Liver-Fibrosis Treatments - Part 1

What is Liver Fibrosis and How is It Different from Cirrhosis?

How does the liver change as we get older?

How is that my LFTs are so good when my viral load is seemly so high?

Comprehensive Care for Chronic Viral Hepatitis

What can Cause Liver Inflammation?  

What Are the Major Functions that the Liver Carries?


 





Co-Infections and Super-Infections of Viral Hepatitis



When a patient with one type of viral hepatitis is infected with different type of hepatitis virus at a later time, it is called a super-infection. (An HCV patient who later acquires HAV for example)

If two different types of hepatitis viruses infect the patient at the same time, it is called a co-infection. (A patient that is infected with HCV and HBV for example)

Co-infections or super-infections with a non-hepatitis virus are also possible, and for HIV population, it is quite common due to the similarities of the infection route. (About 40% of patients with HIV are co-infected with HCV.) For these conditions, the clinical symptoms and disease courses are usually more complex and serious than a single viral infection case.

Although super or co-infections can make the disease more severe and its progression faster, there is also the possibility that one of the agents, such as HCV, could help promote the clearings of the other virus, such as HBV, from the body. HCV could also take over the position of HBV and become the major virus to cause persistent chronic infection. 

The HCV and HBV co-infection is quite common, because they have the same transmission route. The co-infection rate of these two viruses is about 15 to 28%, depending on the regions among chronic hepatitis C patients. Clinically, the co-infection could have more severe symptoms, faster progression, and a higher rate of fulminant hepatitis occurrence.

HAV is usually contracted from contaminated food and water. Thus, it is often a super-infection for patients with chronic HCV or HBV infections. This super-infection can cause prolonged jaundice and ALT elevation and can also trigger inflammation activities of chronic HCV or HBV.

To prevent super-infections, it is highly recommended for chronic hepatitis C patients without antibodies for HBV and HAV to have those vaccinations done. Chronic hepatitis B and C patients should also avoid eating uncooked foods such as raw seafood and meats.

Chinese herbal treatment for co-infections of HCV and HBV is essentially the same protocol because the goal is to control liver inflammation. As such, most of the herbal treatment protocols used for treating HCV infection were borrowed from the treatments of HBV infections. The same principles are also applicable to the super-infection of HAV in HCV and HBV patients. Our treatment is designed to protect liver cell damage, enhance the body's immune response, and halt the progression of the disease. 

For co-infection with HIV, the HIV HAART (highly active antiretroviral therapy) treatments can be very harmful to the liver. After being treated with HAART, I have seen many HIV HCV co-infection patients and their liver enzyme level elevate, with obvious fat deposit in the abdomen and some developing jaundice. In our herbal treatments for HIV, we use Glycyrrhizin, which is also used for HCV and HBV infections. The other herbal remedies used for anti-viral therapies are bitter melon (MC Capsule) and olive leaf (Olivessence Capsule) extracts, and they are also used in our HCV and HBV treatments.

We have seen good results on measuring enzyme levels and symptoms with these herbal protocols, with minimal or no side-effects on the patient.

 

 

Return Home
About HCV
Overview
Causes and Transmission

 
Diagnostic Tests
Antibody
HCV RIBA
HCV RNA 
Viral Load

Viral Genotyping

 
Major Signs
Liver Inflammation
Fibrosis
Cirrhosis

 
Peripheral Signs and Symptoms
Fatigue
Jaundice
Bile Retention
Joint Pains and Skin Rashes
Blood Sugar Instability
Portal Vein Hypertension
Ascites

 
Important Liver Function Test Markers
Overview
ALT and AST
ALP and GGT
Albumin
Bilirubin
PT (Prothrombin Time)
 
Liver Biopsy
Overview
Procedure
Inflammation Grade
Fibrosis Stage
 
Interferon Based Treatment
Overview
Ideal Candidate
Possible Side-effects
 
Liver Support with TCM
Overview
Liver Enzymes
Serum Albumin
Blood Clotting Factors
Bile metabolism
GGT
 
Dietary Considerations
Overview
Proteins
Essential Fats
Carbohydrates
Vitamins
 
 

 


 

 

Medical Information Sources:
http://www.nih.gov/
http://www.nlm.nih.gov/

http://nccam.nih.gov/
http://www.medlineplus.org/


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