Hepatitis C
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Articles by
Dr. Zhang
 
TCM and MCM Theory Related to Common Liver Disease Blood Test Markers

Low Dose Interferon Patient Experiment

Hepatitis A Prevention Reminder

Hepatitis: Causes of Pain in Liver Region 

The Need to Monitor Your Chronic Hepatitis

Liver Enzyme Fluctuation during Allergy Season 

What are the Serum Markers of Hepatitis B and What do They Mean?

Enterogenous Endotoxemia in Chronic Hepatitis–
Part 2

Enterogenous Endotoxemia in Chronic Hepatitis–
Part 1
 

Chronic Hepatitis and "Blood Activating and Stasis Expelling" (BASE) Therapy -
Part 2

Chronic Hepatitis and "Blood Activating and Stasis Expelling" (BASE) Therapy
Part 1

What Causes Gastrointestinal Bleeding in Cirrhotic Liver Disease

Dietary Support for Cirrhotic Liver Diseases

Ascites - A Complication of De-Compensated Liver Cirrhosis

Liver Cirrhosis - Portal Vein Hypertension Complications

Liver Cirrhosis Overview

PG-IFN and Ribavirin Treatments

Antibiotics and Chronic Liver Diseases

Why is Alcohol Harmful for People with Hepatitis?

Co-infections and Super-infections of Viral Hepatitis

Beware of Medications That Can Cause Liver Damage

Bile Retention and Its Clinical Manifestations (MCM) part 4

Modern Chinese Medicine (MCM) Part 3 
Jaundice and Chronic Viral Hepatitis

Modern Chinese Medicine (MCM) Anti-Liver-Fibrosis Treatments - Part 2

Modern Chinese Medicine (MCM) Anti-Liver-Fibrosis Treatments - Part 1

What is Liver Fibrosis and How is It Different from Cirrhosis?

How does the liver change as we get older?

How is that my LFTs are so good when my viral load is seemly so high?

Comprehensive Care for Chronic Viral Hepatitis

What can Cause Liver Inflammation?  

What Are the Major Functions that the Liver Carries?


 

Peripheral Signs and Symptoms
Portal Vein Hypertension


Portal vein hypertension is a common and serious complication of cirrhotic liver disease. Because the blood flow entering the portal vein is being resisted by the inflamed, fibrostic and nodular liver tissue, the pressure in the portal vein is increased. Severe complications can occur as the result of this increased pressure and these include ascites(water retention), gastro-esophageal varices and encephalopathy (mental disorientation).

In viral hepatitis B and C, portal vein hypertension mainly stems from hepatic damages, caused by chronic persistent inflammation and fibrosis in the liver. As the liver inflammation and fibrosis progresses, the pressure in the portal vein will continually rise. When this pressure becomes two times higher than the normal range, collateral complications will start to surface. Under this pressure level, the portal vein and systematic blood vessels form collaterals, which will cause the development of gastro-esophageal varices. Varices are the main contributory factor in bleeding, which is the most serious complication in cirrhotic liver diseases. Another cause of this type of bleeding is the drop of platelet count and reduced production of blood clotting factors in the liver.

When a severe gastro esophageal bleeding occurs, the patient’s stool color will turn shiny black and blood pressure will drop sharply and may cause shock. If this happens, the patient should be rushed to the nearest emergency room immediately.

Another common complication related to the hypertension of portal vein is ascites. In this stage of the liver disease, the liver's ability to synthesize albumin is greatly deteriorated. The resulting low albumin level causes the osmotic pressure of the blood to decrease and the serum’s ability to hold fluid is compromised. Fluid then leaks into the stomach cavity and forms the ascites.

When ascites occurs, the patient should restrict salt intake (salt causes water retention). To treat ascites, the first measure is to improve the overall function of the liver and increase albumin production.
 

 

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About HCV
Overview
Causes and Transmission

 
Diagnostic Tests
Antibody
HCV RIBA
HCV RNA 
Viral Load

Viral Genotyping

 
Major Signs
Liver Inflammation
Fibrosis
Cirrhosis

 
Peripheral Signs and Symptoms
Fatigue
Jaundice
Bile Retention
Joint Pains and Skin Rashes
Blood Sugar Instability
Portal Vein Hypertension
Ascites

 
Important Liver Function Test Markers
Overview
ALT and AST
ALP and GGT
Albumin
Bilirubin
PT (Prothrombin Time)
 
Liver Biopsy
Overview
Procedure
Inflammation Grade
Fibrosis Stage
 
Interferon Based Treatment
Overview
Ideal Candidate
Possible Side-effects
 
Liver Support with TCM
Overview
Liver Enzymes
Serum Albumin
Blood Clotting Factors
Bile metabolism
GGT
 
Dietary Considerations
Overview
Proteins
Essential Fats
Carbohydrates
Vitamins
 
 

 


 

 

Medical Information Sources:
http://www.nih.gov/
http://www.nlm.nih.gov/

http://nccam.nih.gov/
http://www.medlineplus.org/


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