Hepatitis C
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Articles by
Dr. Zhang
TCM and MCM Theory Related to Common Liver Disease Blood Test Markers

Low Dose Interferon Patient Experiment

Hepatitis A Prevention Reminder

Hepatitis: Causes of Pain in Liver Region 

The Need to Monitor Your Chronic Hepatitis

Liver Enzyme Fluctuation during Allergy Season 

What are the Serum Markers of Hepatitis B and What do They Mean?

Enterogenous Endotoxemia in Chronic Hepatitis–
Part 2

Enterogenous Endotoxemia in Chronic Hepatitis–
Part 1

Chronic Hepatitis and "Blood Activating and Stasis Expelling" (BASE) Therapy -
Part 2

Chronic Hepatitis and "Blood Activating and Stasis Expelling" (BASE) Therapy
Part 1

What Causes Gastrointestinal Bleeding in Cirrhotic Liver Disease

Dietary Support for Cirrhotic Liver Diseases

Ascites - A Complication of De-Compensated Liver Cirrhosis

Liver Cirrhosis - Portal Vein Hypertension Complications

Liver Cirrhosis Overview

PG-IFN and Ribavirin Treatments

Antibiotics and Chronic Liver Diseases

Why is Alcohol Harmful for People with Hepatitis?

Co-infections and Super-infections of Viral Hepatitis

Beware of Medications That Can Cause Liver Damage

Bile Retention and Its Clinical Manifestations (MCM) part 4

Modern Chinese Medicine (MCM) Part 3 
Jaundice and Chronic Viral Hepatitis

Modern Chinese Medicine (MCM) Anti-Liver-Fibrosis Treatments - Part 2

Modern Chinese Medicine (MCM) Anti-Liver-Fibrosis Treatments - Part 1

What is Liver Fibrosis and How is It Different from Cirrhosis?

How does the liver change as we get older?

How is that my LFTs are so good when my viral load is seemly so high?

Comprehensive Care for Chronic Viral Hepatitis

What can Cause Liver Inflammation?  

What Are the Major Functions that the Liver Carries?


Major Signs

Liver cirrhosis is developed from fibrosis. Although, fibrosis and cirrhosis are not exactly the same, they are closely related.

At the fibrosis stages, the amount of collagen deposits in the liver increases and the ratio of fibro-connective tissue verses liver cellular tissue increases. But at this stage, the liver lobular structures are intact. There is no pseudo-lobule formation.

Cirrhosis consists of two pathological features: fibro-connective tissue hypertrophy and pseudo-lobule formation. At the cirrhosis stage, the liver's fundamental structure is compromised and deformed, and the framework of the liver begins collapse. Thus, reversal is much more difficult.

Right now a liver biopsy is the most accurate way to diagnose the fibrosis stages. Some blood chemical measurements can also provide a referential diagnostic marker of fibrosis. The chemical markers that can be used to assess the fibrostic activities are: HA (hyaluronic acid), LN (Laminin), CIV(collagen IV), PCIII (procollagen type III) etc. They can show the activities of fibrosis, but can't classify stages of fibrosis.

There are newly developed types of blood tests such as Fibrotest used to assess liver fibrosis activity. However, the accuracy has not quite matched the traditional liver biopsy as of yet.

Patients should also understand that 80% to 85% of chronic hepatitis cases will not lead to cirrhosis. Only a very small percentage does and it happens usually without proper treatment, allowing fibrosis to go on for years.

The body has amazing healing capabilities of its own and the liver is one of the most “re-generable” organs in the body. Because fibrosis is the result of the inflammation, halting or reversing fibrosis by controlling inflammation is the key.


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About HCV
Causes and Transmission

Diagnostic Tests
Viral Load

Viral Genotyping

Major Signs
Liver Inflammation

Peripheral Signs and Symptoms
Bile Retention
Joint Pains and Skin Rashes
Blood Sugar Instability
Portal Vein Hypertension

Important Liver Function Test Markers
PT (Prothrombin Time)
Liver Biopsy
Inflammation Grade
Fibrosis Stage
Interferon Based Treatment
Ideal Candidate
Possible Side-effects
Liver Support with TCM
Liver Enzymes
Serum Albumin
Blood Clotting Factors
Bile metabolism
Dietary Considerations
Essential Fats




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