Hepatitis C
Return To SinoMed Main
Information presented on this website is for educational purposes only.
Materials presented have not been evaluated by the U.S. Food & Drug Administration and are not meant as a replacement or substitute for professional medical diagnosis and treatment. Visitors are advised to seek professional medical care for any any disease or illness.



Articles by
Dr. Zhang
TCM and MCM Theory Related to Common Liver Disease Blood Test Markers

Low Dose Interferon Patient Experiment

Hepatitis A Prevention Reminder

Hepatitis: Causes of Pain in Liver Region 

The Need to Monitor Your Chronic Hepatitis

Liver Enzyme Fluctuation during Allergy Season 

What are the Serum Markers of Hepatitis B and What do They Mean?

Enterogenous Endotoxemia in Chronic Hepatitis–
Part 2

Enterogenous Endotoxemia in Chronic Hepatitis–
Part 1

Chronic Hepatitis and "Blood Activating and Stasis Expelling" (BASE) Therapy -
Part 2

Chronic Hepatitis and "Blood Activating and Stasis Expelling" (BASE) Therapy
Part 1

What Causes Gastrointestinal Bleeding in Cirrhotic Liver Disease

Dietary Support for Cirrhotic Liver Diseases

Ascites - A Complication of De-Compensated Liver Cirrhosis

Liver Cirrhosis - Portal Vein Hypertension Complications

Liver Cirrhosis Overview

PG-IFN and Ribavirin Treatments

Antibiotics and Chronic Liver Diseases

Why is Alcohol Harmful for People with Hepatitis?

Co-infections and Super-infections of Viral Hepatitis

Beware of Medications That Can Cause Liver Damage

Bile Retention and Its Clinical Manifestations (MCM) part 4

Modern Chinese Medicine (MCM) Part 3 
Jaundice and Chronic Viral Hepatitis

Modern Chinese Medicine (MCM) Anti-Liver-Fibrosis Treatments - Part 2

Modern Chinese Medicine (MCM) Anti-Liver-Fibrosis Treatments - Part 1

What is Liver Fibrosis and How is It Different from Cirrhosis?

How does the liver change as we get older?

How is that my LFTs are so good when my viral load is seemly so high?

Comprehensive Care for Chronic Viral Hepatitis

What can Cause Liver Inflammation?  

What Are the Major Functions that the Liver Carries?


Liver Support with TCM
Bile Metabolism
This information is for educational purposes only.
Materials regarding herbs have not been evaluated by the
U.S. Food & Drug Administration and are not in any way a replacement or substitute for professional medical diagnosis and treatment. Persons with specific medical illnesses are advised to seek professional care.

Bile acid is synthesized in the liver. Its metabolism in the body is mainly controlled by the liver and can therefore reflect its functional status. Everyday, the liver processes more than 18 to 24 grams of bile acid, which is 100 times more than bilirubin. Its serum level elevates to the highest levels in viral hepatitis and extra-liver bile duct stenosis. For chronic hepatitis patients, serum bile acid level usually elevates before the elevation of ALT and AST. After treatment, if the level of serum bile acid continues to elevate even as the histological markers in a liver biopsy improve, the possibility of relapse is still high. In bile retention liver diseases, such as PBC and PSC, serum bile acid level is usually obviously elevated.

In fatty liver or mild chronic hepatitis, bile acid change is usually not as sensitive as changes in ALT and AST markers. But in serious liver diseases, such as cirrhosis, bile acid is more sensitive than the enzymes. The enzymes only reflect the liver cell damage at the moment while bile acid can also reflect the absorption and secretion abilities of the intestines and the liver, and possible existence of portal-systemic circulation bypasses. In predicting liver failure, serum bile acid is a more sensitive indicator than bilirubin.

Clinically, when using TCM to treat bile acid abnormalities, both Qi and blood should be treated according to TCM theory. When there is bilirubin elevation, it is usually accompanied by ALT and AST elevation. For this condition, the treatment method should be “heat clearing and dampness eliminating.” The commonly used herbal formulas are
Yin Chen Wu Ling San (Capillaris and Hoelen Five Formula)
Wu Wei Xiao Du Yin (Decoction of Five Ingredients for Antiphologistic).

When these formulas are used, large doses of Yin Chen Hao (Artemisiae Capillaris), and medium to small doses of Jin Qian Cao (Desmodii Herba) and Da Huang (Rhei Rhizoma) should also be used.

If bilirubin elevation is accompanied by bile acid and GGT elevation, treatment must also focus on improving blood circulation and anti-fibrosis actions. The herbs must have both jaundice clearing and blood activating effects.

Examples are:
Hu Zhang (Polygoni Cuspidati Rhizoma)
Qian Cao (Rubiae radix)
Yin Chen Hao (Artemisiae Capillaris)
Da Huang (Rhei Rhizoma).

[Liu YL et al., Premary Discusion on the Use of Chinese Medicine According to Blood Tests, CJITWM, Jan 2003, 23(1):54-55]

Return Home
About HCV
Causes and Transmission

Diagnostic Tests
Viral Load

Viral Genotyping

Major Signs
Liver Inflammation

Peripheral Signs and Symptoms
Bile Retention
Joint Pains and Skin Rashes
Blood Sugar Instability
Portal Vein Hypertension

Important Liver Function Test Markers
PT (Prothrombin Time)
Liver Biopsy
Inflammation Grade
Fibrosis Stage
Interferon Based Treatment
Ideal Candidate
Possible Side-effects
Liver Support with TCM
Liver Enzymes
Serum Albumin
Blood Clotting Factors
Bile metabolism
Dietary Considerations
Essential Fats




Medical Information Sources:


Contact the Webmaster

Copyright © 2005 Sinomed Research Institute®